The Affymetrix GeneChip® Human Mapping 10K Array Xba 142
2.0 provides comprehensive single nucleotide polymorphism (SNP) genotyping
across the human genome at a median intermarker distance of 105 kb. Only
250 ng of genomic DNA are required to obtain more than 10.000 genotypes.
The Affymetrix GeneChip® Human Mapping 100K Set is
comprised of two arrays, each with greater than 50.000 SNPs. One array uses
the XbaI restriction
enzyme, while the second uses HindIII. With 100.000 SNPs obtained in
a single experiment at a median intermarker distance of 8.5 kb, the Mapping
100K Set is the first in a family of products for whole-genome association
studies (Comparison of Mapping 10K and 100K SNP coverage to 400 marker
microsatellite panel).
The GeneChip® Mapping products are the ideal
tools for:
The Large-Scale Genotyping Service follows this general workflow (technology and graphical overview
- example given for the Mapping 10K 2.0 Array):
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