Affymetrix GeneChip® Technology

Affymetrix GeneChip® Technology supports both RNA (Gene Expression) and DNA (Genotyping, Resequencing) analysis. The high density of GeneChip® arrays, the high reproducibility and the low amount of biological specimen needed are clear advantages of GeneChip® Technology over alternative microarray platforms and have made it the gold standard in this field.

For the production of GeneChip® arrays a combination of photolithography and combinatorial chemistry is used to synthesize millions of copies of selected oligonucleotides (25 nucleotides in final length) base by base in hundreds of thousands of different probe cells on a glass surface. Probe cells have a size of only 11 µm x 11 µm in the most recent GeneChip® array design.